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Carney Complex Complicated with Primary Pigmented Nodular Adrenocortical Disease without Cushing's Syndrome
Yuya Tsurutani1, Kanako Kiriyama1, Mai Kondo1
1Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Japan.
Abstract:
We herein report a case of Carney complex (CNC) complicated with primary pigmented nodular adrenocortical disease (PPNAD) after unilateral adrenalectomy. A 44-year-old woman was admitted to our hospital for PPNAD surgery. She had previously undergone surgery for cardiac myxoma and had a PRKAR1A mutation with no family history of CNC. She had Cushing's signs, but her metabolic abnormalities were mild. Adrenal insufficiency due to poor medication adherence was a concern, so she underwent unilateral adrenalectomy. Cushing's signs improved postoperatively and without recurrence for five years. Treatment plans for PPNAD should be determined based on the patient's condition, medication adherence, and wishes.
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