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Severe Acute Respiratory Syndrome Type 2-Causing Coronavirus: Variants and Preventive Strategies
Mehmet Onur Aydogdu1, Jennifer L Rohn2, Nazila V Jafari2
1Department of Mechanical Engineering, University College London (UCL), Torrington Place, London, WC1E 7JE, UK.
Abstract:
COVID-19 vaccines have constituted a substantial scientific leap in countering severe acute respiratory syndrome type 2-causing coronavirus (SARS-CoV-2), and worldwide implementation of vaccination programs has significantly contributed to the global pandemic effort by saving many lives. However, the continuous evolution of the SARS-CoV-2 viral genome has resulted in different variants with a diverse range of mutations, some with enhanced virulence compared with previous lineages. Such variants are still a great concern as they have the potential to reduce vaccine efficacy and increase the viral transmission rate. This review summarizes the significant variants of SARS-CoV-2 encountered to date (December 2021) and discusses a spectrum of possible preventive strategies, with an emphasis on physical and materials science.
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