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Updated: Oct 6, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Spironolactone in dermatology.

Diana Alejandra Aguilar Medina¹, Jorge Cazarín¹, Mario Magaña¹

¹Service of Dermatology, Hospital General de Mexico "Dr. Eduardo Liceada", S.S. Ministry of Health, Mexico City, Mexico.

Dermatologic Therapy

|January 17, 2022

Summary

Spironolactone, an aldosterone antagonist, shows promise for treating dermatological conditions like acne and hirsutism. This review explores its efficacy, dosage, and recommendations for clinical use.

Keywords:

acne androgenetic alopecia hidradenitis suppurativa hirsutism polycystic ovary syndrome spironolactone

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Area of Science:

Dermatology
Pharmacology

Background:

Spironolactone is an aldosterone receptor antagonist with anti-androgenic properties.
Its therapeutic potential in dermatology is recognized but not fully explored.

Purpose of the Study:

To review the use of spironolactone in common dermatological conditions.
To provide guidance on dosage, treatment recommendations, and adverse effects for clinical practice.

Main Methods:

Literature review of studies on spironolactone in dermatology.
Analysis of reported dosages, treatment outcomes, and side effects.

Main Results:

Spironolactone is effective in treating acne, hidradenitis suppurativa, hirsutism, and female pattern androgenetic alopecia.
Evidence suggests potential for spironolactone as a first-line treatment in certain cases.

Conclusions:

Spironolactone is a valuable therapeutic option for various dermatological conditions.
Further research and clinical experience can optimize its application in daily practice.