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Updated: Oct 6, 2025

The use of Biofeedback in Clinical Virtual Reality: The INTREPID Project
Published on: November 12, 2009
Therapeutic use of virtual reality relaxation in schizophrenia: A pilot study
Ophélie Rault1, Hugues Lamothe2, Antoine Pelissolo2
1Psychiatry and Addictology Service, AP-HP, Hôpital Paul Brousse, Univ Paris-Saclay, Villejuif 94800, France.
Abstract:
Virtual reality can be used for psychotherapeutic purposes. Our main objective is to assess the feasibility and the tolerance of a relaxation therapy in virtual reality from patients suffering from schizophrenia, by studying the risks of symptoms of depersonalization or cybersickness. It is a prospective, open, five-week clinical study. Evaluations were carried out before and after each session. They were 13 patients aged 18 to 65. Analyzes showed a good tolerance and acceptance regarding virtual reality and anxiolytic effects have been observed between baseline values and those obtained after the first session and after the fifth session (p < 0.05).

