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Related Experiment Videos

Tardive myoclonus.

J T Little1, J Jankovic

  • 1Department of Neurology, Baylor College of Medicine, Houston, Texas 77030.

Movement Disorders : Official Journal of the Movement Disorder Society
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

This case study reports a rare instance of late-onset myoclonus in a schizophrenic woman, which continued even after antipsychotic drug discontinuation. This suggests a potential new neurological side effect of these medications.

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Area of Science:

  • Neurology
  • Psychiatry
  • Pharmacology

Background:

  • Schizophrenia is a chronic mental disorder often treated with antipsychotic medications.
  • Antipsychotic drugs can cause various side effects, including movement disorders.

Observation:

  • A 46-year-old woman with schizophrenia developed late-onset myoclonus.
  • The myoclonic jerking affected the neck and face.
  • Symptoms persisted after discontinuing all antipsychotic treatments.

Findings:

  • This case presents a previously undocumented form of tardive myoclonus.
  • The persistent nature of the myoclonus suggests a potential long-term neurological impact.

Implications:

  • This finding may expand the spectrum of known adverse drug reactions to antipsychotics.
  • Further research is needed to understand the pathophysiology and prevalence of tardive myoclonus.