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Torticollis following radiation therapy
1Department of Neurology, Wayne State University, School of Medicine, Detroit, Michigan.
Summary
Radiation therapy for lung cancer can lead to torticollis, a neck condition. This occurs due to radiation-induced fibrosis and potential nerve damage, causing a peripheral nervous system lesion.
Area of Science:
- Neurology
- Oncology
- Radiotherapy
Background:
- Pancoast's syndrome, often associated with apical lung adenocarcinoma, presents unique clinical challenges.
- Radiation therapy is a standard treatment for lung malignancies, but potential side effects require careful consideration.
Observation:
- A patient with lung adenocarcinoma and Pancoast's syndrome developed torticollis after radiation therapy to the neck and upper chest.
- The onset of torticollis occurred several months post-radiation treatment.
Findings:
- The torticollis is hypothesized to result from local radiation fibrosis affecting neck muscles.
- Segmental demyelination of the 11th cranial nerve is also considered a potential contributing factor to the peripheral nervous system lesion.
Implications:
- This case highlights a rare complication of radiation therapy, emphasizing the need for monitoring neurological function post-treatment.
- Understanding the mechanisms of radiation-induced peripheral nerve damage is crucial for managing treatment side effects in cancer patients.