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Vidarabine encephalopathy.

P A Cullis, R Cushing

Journal of Neurology, Neurosurgery, and Psychiatry

|December 1, 1984

Summary

This summary is machine-generated.

Vidarabine, an antiviral medication, can cause neurological side effects like tremor and encephalopathy. This review discusses two new cases and five previously reported instances of vidarabine encephalopathy.

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Area of Science:

Neuroscience
Pharmacology
Virology

Background:

Vidarabine (adenine arabinoside, ara-a) is an antiviral agent used for treating various viral infections.
Neurological adverse effects, including tremor and encephalopathy, are known complications of vidarabine therapy.

Observation:

Two new cases of vidarabine-induced encephalopathy are presented.
A review of five additional cases from existing literature is included.

Findings:

The clinical manifestations of tremor and encephalopathy associated with vidarabine treatment are analyzed.
The reported cases highlight the spectrum of neurological toxicity from vidarabine.

Implications:

Understanding these neurological effects is crucial for safe vidarabine administration.

Further research may elucidate mechanisms and management strategies for vidarabine neurotoxicity.