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Invasive Mucormycosis - An Enigma
Anil Prasad1, Minakshi Mishra1, Kaushik Saha1
1Pathology, Tata Main Hospital, Jamshedpur, IND.
Abstract:
Mucormycosis is an emerging infection in the present post-COVID-19 era, associated with high morbidity and mortality. We are reporting an interesting case of invasive rhino-orbital-cerebral mucormycosis in a 65-year-old female who presented with left nasal and orbital swelling after COVID-19 infection associated with uncontrolled diabetes mellitus. Histopathological and microbiology examination favored mucormycosis. Finally, endoscopic debridement of the lesion was done with left orbital exenteration. The patient at present is clinically stable. As these cases have been seen in many suspected and confirmed COVID-19 cases, early diagnosis and treatment will salvage the patient.
Insights
Mucormycosis, a serious fungal infection, is emerging in the post-COVID-19 period, particularly in individuals with uncontrolled diabetes. Early diagnosis and treatment of invasive rhino-orbital-cerebral mucormycosis are crucial for patient survival.
Area of Science:
- Infectious Diseases
- Ophthalmology
- Neurosurgery
Background:
- Mucormycosis is a severe fungal infection with high mortality rates.
- The incidence of mucormycosis is increasing in the post-COVID-19 era.
- Uncontrolled diabetes mellitus is a significant risk factor.
Observation:
- A 65-year-old female presented with left nasal and orbital swelling following COVID-19 infection.
- The patient had a history of uncontrolled diabetes mellitus.
- Clinical presentation suggested invasive rhino-orbital-cerebral mucormycosis.
Findings:
- Histopathological and microbiological examinations confirmed mucormycosis.
- The patient underwent endoscopic debridement and left orbital exenteration.
- The patient's current clinical condition is stable.
Implications:
- This case highlights the critical link between COVID-19, diabetes, and mucormycosis.
- Prompt diagnosis and aggressive management are essential for improving outcomes.
- Increased vigilance for mucormycosis in immunocompromised patients post-COVID-19 is warranted.
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Fungal Group Zygomycota
Fungal Phylum Ascomycota
Fungal Phylum Microsporidia
Fungal Phylum Basidiomycota

