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A core outcome set for damage control laparotomy via modified Delphi method.

Saskya Byerly1, Jeffry Nahmias2, Deborah M Stein3

  • 1Surgery, University of Tennessee Health Science Center, Memphis, TN, USA.

Trauma Surgery & Acute Care Open
|January 20, 2022
PubMed
Summary
This summary is machine-generated.

Experts established a core outcome set for damage control laparotomy (DCL) research. This standardized approach will improve data analysis and reduce bias in future trauma surgery studies.

Keywords:
abdominal injurieslaparotomypatient outcome assessment

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Area of Science:

  • Trauma Surgery
  • Surgical Outcomes Research
  • Clinical Trial Methodology

Background:

  • Damage control laparotomy (DCL) is a critical trauma surgery technique.
  • Inconsistent outcome reporting hinders DCL research and data pooling.
  • Standardized outcome measures are needed for robust meta-analysis and Bayesian statistics.

Purpose of the Study:

  • To develop a core outcome set (COS) for clinical studies involving damage control laparotomy.
  • To standardize outcome reporting in DCL research.
  • To facilitate data aggregation and reduce bias in future DCL studies.

Main Methods:

  • A modified Delphi study involving content experts in DCL.
  • Experts were identified from Eastern Association for the Surgery of Trauma (EAST) publications and task forces.
  • A three-round electronic survey process was used to reach consensus.

Main Results:

  • Twenty content experts participated, with high engagement across three rounds.
  • Consensus was reached on 10 core outcomes, including mortality, fascial closure, abdominal complications, and functional outcomes.
  • No further consensus was achieved in round 3 on additional outcomes.

Conclusions:

  • A consensus-based core outcome set for damage control laparotomy research was established.
  • This COS is recommended for adoption in future DCL clinical trials.
  • Further research is needed to define specific measurement tools for these core outcomes.