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In Vivo Organic Bioelectronics for Neuromodulation
Magnus Berggren1, Eric D Głowacki1,2, Daniel T Simon1
1Laboratory of Organic Electronics, Department of Science and Technology, Linköping University, 601 74 Norrköping, Sweden.
Chemical Reviews
|January 20, 2022
Summary
Organic electronics can translate electronic signals into neurobiological language, enabling advanced neuroprosthetics and therapies. This technology bridges the gap between electronics and the nervous system for better integration.
Area of Science:
- Neuroscience
- Materials Science
- Biomedical Engineering
Background:
- The nervous system's complexity challenges integration with modern electronics.
- Conventional electronics require a translation layer for neurobiological signaling.
Purpose of the Study:
- To review organic electronics as a "translator" for nervous system integration.
- To highlight organic material platforms and signaling modalities for neuromodulation.
Main Methods:
- Review of existing literature on organic electronics for neural interfaces.
- Focus on organic material platforms and signaling modalities.
- Emphasis on in vivo neuromodulation applications.
Main Results:
- Organic electronics can mimic endogenous neural signaling.
- Favorable material properties of organic electronics for tissue compatibility.
- Demonstrated potential in in vivo neuromodulation.
Conclusions:
- Organic electronics offer a promising solution for interfacing electronics with the nervous system.
- Further development is encouraged for advanced neuroprosthetics and therapies.
