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Gastrointestinal motility in constipation.

B M Silva-Neto¹, I Cecconello, A Habr-Gama

¹Brazilian Institute for Studies and Research in Gastroenterology.

Arquivos De Gastroenterologia

|July 1, 1987

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Constipation is linked to altered colonic motility and transit. Patients with constipation exhibit faster proximal sigmoid contrast arrival and slower overall gastrointestinal emptying, alongside increased sigmoid and rectal motility.

Area of Science:

Gastroenterology
Colorectal Physiology

Background:

Constipation is a common condition affecting gastrointestinal motility.
Understanding the physiological basis of constipation is crucial for effective treatment.

Purpose of the Study:

To investigate differences in gastrointestinal transit times and colonic motility between individuals with and without constipation.
To elucidate the specific mechanisms contributing to delayed transit in constipation.

Main Methods:

Gastrointestinal transit time assessment using X-rays.
Intraluminal pressure measurements in the sigmoid colon and rectum via electromanometry.
Comparison of data between a control group and patients with constipation.

Main Results:

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No significant difference in cecal transit times between groups.
Faster arrival of barium contrast in the proximal sigmoid for constipation patients.
Slower overall gastrointestinal emptying time in patients with constipation.
Elevated motility index in the sigmoid and rectum of constipation patients under unstimulated conditions.
Increased colonic propulsion and retention activities in constipation.

Conclusions:

Constipation is characterized by altered colonic motor activity and transit dynamics.
Increased motility index, particularly percent activity, contributes to constipation.
Radiologic and electromanometric findings highlight enhanced propulsion and retention in constipated individuals.