Related Experiment Video
Updated: Oct 6, 2025

Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
Carbon dioxide redox metabolites in oxidative eustress and oxidative distress
Ohara Augusto1, Daniela Ramos Truzzi1
1Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Abstract:
High carbon dioxide tensions (hypercapnia) are toxic to mammals by both pH-dependent and pH-independent mechanisms that remain partially understood. Relevantly, carbon dioxide reacts with biologically ubiquitous oxygen metabolites such as peroxynitrite and hydrogen peroxide to produce carbonate radical and peroxymonocarbonate, respectively. These metabolites are redox active making it timely to discuss the potential role of carbon dioxide redox metabolites in oxidative eustress and oxidative distress conditions.
Related Concept Videos
Redox Reactions
Oxidation and Reduction of Organic Molecules
The removal of an electron from a molecule, results in a...
Redox Equilibria: Overview
Electron Transport Chain: Complex III and IV
Oxygen Requirements and Growth Patterns
The Supercomplexes in the Crista Membrane

