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Updated: Oct 6, 2025

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
IgG4-Related Disease Affecting Testicle and Myelodysplastic Syndrome: Just a Coincidence?
Carla Alvarez Gonzalez1, Juan Luis Carrillo Linares1, Isabel García Muñoz2
1Department of Internal Medicine, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
Abstract:
Immunoglobulin G4-related disease (IgG4-RD) is progressive immune-mediated fibrotic condition characterised by a tendency to form tumefactive lesions in different organs and by elevated IgG4 serum concentrations. Urological manifestations are rare and normally occur together with other systemic affections. Myelodysplastic syndromes (MDS) are hematopoietic stem cell neoplasms, with different subtypes based on the type of blood cells involved. MDS can be associated with other pathologies or medical treatments. We present an uncommon case of testicular manifestation associated with myelodysplastic syndrome here.
Learning Points:
Testicular inflammation is a manifestation of IgG4-related disease.Testicular inflammation and myelodysplastic syndrome can simultaneously present.

