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Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
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Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

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The importance of myocarditis in Covid-19

Katayoun Haryalchi1, Sepehr Olangian-Tehrani2, Seyed Mohammad Asgari Galebin3

  • 1Reproductive Health Research Center, Al-zahra Hospital, School of Medicine Guilan University of Medical Sciences Rasht Iran.

Health Science Reports
|January 21, 2022
PubMed

Insights

The Covid-19 virus can cause serious heart complications, including myocarditis. This study reviews how the virus impacts myocarditis and its associated cardiac injuries.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • The novel coronavirus (Covid-19) outbreak poses a significant public health threat.
  • Covid-19 is associated with cardiovascular complications, notably acute myocardial injury and myocarditis.
  • Myocarditis symptoms include chest pain, tachycardia, and chest tightness, potentially leading to cardiogenic shock.

Purpose of the Study:

  • To assess the effects of Covid-19 on myocarditis.
  • To review the mechanisms of cardiac injury in Covid-19 patients.
  • To discuss current treatment protocols and research gaps.

Main Methods:

  • This study employed a narrative review methodology.
  • Literature search was conducted on Covid-19 and myocarditis.
  • Existing research on cardiac injury mechanisms and treatment was synthesized.

Main Results:

  • Cardiac injury in Covid-19 may result from direct viral myocardial infection, hypoxemia, or systemic inflammation.
  • Pathologic processes include viral binding to ACE2 receptors, systemic inflammation, and thrombosis.
  • There is ongoing debate regarding corticosteroid use in active Covid-19 myocarditis.

Conclusions:

  • Covid-19 presents a multifaceted threat to cardiovascular health, particularly concerning myocarditis.
  • Further research is crucial to understand and manage Covid-19-related cardiac complications.
  • Clarifying treatment strategies, such as corticosteroid use, is essential.
Abstract

Keywords:
Covid‐19heartmyocarditis

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