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Related Concept Videos

Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

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An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
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Esophagus01:24

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The esophagus, a muscular conduit linking the pharynx and stomach, measures roughly 10 inches (25.4 cm) and sits behind the trachea. It remains collapsed when not swallowing. The esophagus follows a predominantly straight path through the thoracic mediastinum and enters the abdominal cavity through a diaphragmatic opening known as the esophageal hiatus.
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
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Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
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Endoscopic Procedures III: Video Capsule Endoscopy01:28

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Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
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Esophageal Strictures-II: Clinical Features and Management01:26

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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Barrett Esophagus-II: Clinical Manifestations and Management01:21

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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
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Related Experiment Video

Updated: Oct 6, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

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Devices for esophageal function testing.

Rahul Pannala1, Kumar Krishnan2, Rabindra R Watson3

  • 1Department of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, Arizona.

Videogie : an Official Video Journal of the American Society for Gastrointestinal Endoscopy
|January 21, 2022
PubMed
Summary
This summary is machine-generated.

Esophageal function tests like functional luminal imaging probe (FLIP) and high-resolution manometry (HRM) aid in diagnosing GERD and motility disorders. These advanced tools improve understanding and management of complex esophageal conditions.

Keywords:
AET, acid exposure timeASGE, American Society for Gastrointestinal EndoscopyBMI, body mass indexCC, Chicago classificationCD, contractile decelerationCSA, cross-sectional areaDI, distensibility indexDP, distensibility plateauDRI, dysphagia risk indexEGJ, esophagogastric junctionEGJOO, esophagogastric junction outflow obstructionEM, esophageal manometryEPT, esophageal pressure topography plotsEoE, eosinophilic esophagitisFLIP, functional luminal imaging probeHRM, high-resolution esophageal manometryIEM, ineffective esophageal motilityIRP, integrated relaxation pressureLES, lower esophageal sphincterLHM, laparoscopic Heller myotomyMII, multichannel intraluminal impedanceMRS, multiple rapid swallowsMSA, magnetic sphincter augmentationNOD, nonobstructive dysphagiaPOEM, peroral endoscopic myotomyPPI, proton pump inhibitorsSAP, symptom association probabilitySI, Symptom indexUES, upper esophageal sphincter

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Area of Science:

  • Gastroenterology
  • Gastrointestinal Physiology
  • Medical Technology

Background:

  • Esophageal function testing is crucial for evaluating refractory gastroesophageal reflux disease (GERD) and esophageal motility disorders.
  • Current technologies include functional luminal imaging probe (FLIP), high-resolution esophageal manometry (HRM), and multichannel intraluminal impedance (MII) and pH monitoring.

Purpose of the Study:

  • To review and summarize current esophageal function testing technologies.
  • To highlight the diagnostic and prognostic value of these techniques in clinical practice.

Main Methods:

  • Literature search of MEDLINE, PubMed, and MAUDE databases through March 2021.
  • Inclusion of studies using keywords: esophageal manometry, HRM, esophageal impedance, FLIP, MII, and esophageal pH testing.
  • Gathering technical data from publications and vendor communications.

Main Results:

  • Functional luminal imaging probe (FLIP) measures pressure and dimensions, complementing HRM for motility disorders like achalasia.
  • High-resolution manometry (HRM) data, interpreted using the Chicago classification, aids in diagnosing esophageal motility disorders.
  • Multichannel intraluminal impedance (MII) and pH monitoring detect bolus transit and reflux, valuable for refractory GERD and pre-surgical evaluation.

Conclusions:

  • Esophageal function testing techniques (FLIP, HRM, MII-pH) possess significant diagnostic and prognostic value.
  • Advancements in technology and classification systems enhance the understanding and management of esophageal motility disorders and refractory GERD.