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Generalized pustular psoriasis in Brazil: A public claims database study.
Gleison Vieira Duarte1, André Vicente Esteves de Carvalho2,3, Ricardo Romiti4
1Instituto Bahiano de Imunoterapia - IBIS, Salvador, Brazil.
JAAD International
|January 21, 2022
Summary
Generalized pustular psoriasis (GPP) is rare in Brazil, affecting all ages and sexes. Prompt diagnosis and effective treatment are crucial due to hospitalizations and deaths.
Area of Science:
- Dermatology
- Epidemiology
- Public Health
Background:
- Generalized pustular psoriasis (GPP) is a severe, rare psoriasis variant.
- Characterized by widespread pustules and systemic symptoms.
Purpose of the Study:
- Describe GPP epidemiology in Brazil.
- Analyze GPP treatment from a public healthcare perspective.
Main Methods:
- Retrospective study using public claims databases (2018-2020).
- Analyzed outpatient and inpatient data for GPP patients.
- Described treatment regimens and inpatient outcomes.
Main Results:
- Estimated GPP prevalence: 0.7-0.9 per 100,000 in Brazil.
- Acitretin was the most common outpatient drug.
- 5.3% of hospitalized GPP patients had fatal outcomes; infections were common causes.
Conclusions:
- GPP affects all demographics in Brazil.
- Highlights the need for timely GPP diagnosis and management.
- Urgent need for validated GPP diagnostic codes.
Keywords:
Brazilian public health systemDATASUSDATASUS, Departamento de Informática do Sistema Único de SaúdeGPP, generalized pustular psoriasisICD, International Classification of DiseasesPV, psoriasis vulgarisSIA, Sistema de Informações AmbulatoriaisSIH, Sistema de Informações HospitalaresSUS, Sistema Único de Saúdeclaims database studyepidemiologygeneralized pustular psoriasispsoriasis hospitalizationpsoriasis treatmentpustular psoriasis
