Method R: Efficacy of a cosmetic routine comprising six topical lipid-encapsulated products

Efficacy of cosmetic routines is reportedly available in several dermatological conditions, such as acne or rosacea. However, clinical evidence about objective advantages of skincare routine remains limited despite advertising often claims benefits.

We aimed to assess the subject satisfaction level and the benefit from daily use of an advanced skincare routine named Method R. We used four different approaches to try and demonstrate the efficacy of the method: Transdermal delivery test, ex-vivo efficacy test, Visioscan^® VC 20, and patient survey. MetR consists of a six-step routine that shows an increased epidermal penetration and activity due to liposomation.

Transdermal delivery test and ex-vivo efficacy test show increased efficacy for liposomated actives. The skincare routine is well tolerated, and is associated with a marked efficacy in global quality of skin, dyschromia/pigmentation, brightness, and hydration according to patient perception. The subject satisfaction level is high and the routine is safe. The continuous use of the routine for one month or more results in objective changes when measured with Visioscan^® VC 20 plus.