Related Experiment Video
Updated: Oct 5, 2025

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
A new method for objectively evaluating nocturnal cough in adults
Kota Hirai1, Masanori Ishimaru2, Masahiko Kato1
1Department of Pediatrics, Tokai University School of Medicine, Japan; Department of Pediatrics, Tokai University Hachioji Hospital, Japan.
A new cough monitoring system accurately measures nocturnal coughs in adults. This objective method is highly useful for managing cough diseases.
Area of Science:
- Medical Devices
- Pulmonology
- Biomedical Engineering
Background:
- Objective evaluation of nocturnal cough is crucial for managing adult cough diseases.
- Current methods may lack objectivity in assessing nighttime cough frequency.
Purpose of the Study:
- To evaluate and validate a novel cough monitoring system for objective nocturnal cough assessment in adults.
- To determine the system's accuracy and reliability compared to established methods.
Main Methods:
- Study 1: Assessed a cough monitoring system with 25 adult volunteers.
- Study 2: Validated the system using overnight recordings from 10 adult patients with cough diseases.
- Compared system data against manual counts from video-audio recordings and basal cough events.
Main Results:
- The cough monitoring system showed high sensitivity (99.2%) and specificity (98.9%) in Study 1.
- Significant agreement was found between the system and video-audio counts (p < 0.0001) in Study 2.
- Excellent agreement was observed between the system and basal cough events (p < 0.0001).
Conclusions:
- The developed cough monitoring system demonstrates excellent agreement with video-audio recording methods.
- This system provides a highly useful and objective tool for monitoring overnight cough in adult patients.
- The technology supports improved management strategies for various cough-related conditions.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...
Assessment of Respiration
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
Physical Assessment of the Respiratory Tract IV: Auscultation
Breath Sounds
Breath sounds are categorized into vesicular, bronchovesicular, and bronchial.
Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:

