Related Experiment Video
Updated: Oct 5, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
Bibliometric analysis of research on thyroid ultrasonography
Juan Su1, Guanghui Gao2, Hongxia Xu1
1Department of Ultrasonography, Jinan Central Hospital, Jinan, China.
Background:
The incidence of thyroid diseases has increased, which may be partly related to the widespread use of thyroid ultrasound resulting in a large number of asymptomatic thyroid nodules to be found. Research has found that many thyroid ultrasound examinations are completely avoidable. However, the purpose of the present study was to use bibliometrics to analyze the relevant research literature of thyroid ultrasound and understand the overall status of the current research in this field.
Methods:
We searched the Science Citation Index Expanded (SCI-E) database in the Web of Science Core Collection. Search terms were "ultrasonography" and "thyroid gland". The date range for the document search was from 1900 to May 10, 2021. Export the full record of the search results and the references in txt. format, and use the CiteSpace software to analyze the annual publication of literatures, the distribution of countries and institutions where the literatures came from, the distribution of journals and authors. The keywords used in the literature were also analyzed.
Results:
A total of 1,241 publications were included in the results, and the frequency of citations was 27,149. The top 5 countries for the number of publications published were the USA, Turkey, Italy, South Korea, and China; the top 5 countries by centrality were the USA, Germany, Italy, Canada, and China. The number of institution-published papers was generally low, and the centrality score was low. Research in this field was relatively scattered among institutions and cooperation between institutions was few. There was little collaboration between authors from different institutions. The most cited authors were mainly from European and North American countries. Journals, such as Thyroid, Journal of Clinical Ultrasound, and Journal of Endocrinological Investigation, had great influence in this field. Keyword analysis results showed that research is mainly focused on the differentiation of benign and malignant thyroid nodules.
Conclusions:
There was an increase in thyroid ultrasound research, but there was few cooperation exist between institutions. The main research direction was the differentiation of benign and malignant thyroid nodules.
Related Concept Videos
Ultrasonography
During an ultrasonography procedure, a handheld device called...
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Imaging Studies II: Ultrasonography
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Ultrasound I: Abdominal Ultrasonography
Abdominal ultrasonography, commonly known as abdominal ultrasound, is a vital, non-invasive medical imaging technique widely used in healthcare.
Procedure:
This diagnostic tool allows the clinician to visually inspect internal structures within the abdomen, including vital organs such as the liver, gallbladder, pancreas, kidneys, and spleen.
The abdominal ultrasound process begins with applying a special gel to the patient's skin over the abdomen. This gel enhances the...

