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COVID-19 associated Paediatric Inflammatory Multisystem Syndrome (PIMS) in children

J Klučka, M Kratochvíl, P Dominik

    Epidemiologie, Mikrobiologie, Imunologie : Casopis Spolecnosti Pro Epidemiologii a Mikrobiologii Ceske Lekarske Spolecnosti J.E. Purkyne
    |January 25, 2022
    PubMed

    Insights

    Paediatric Inflammatory Multisystem Syndrome (PIMS) is a rare but serious complication of COVID-19 in children. This report details the first critically ill pediatric PIMS cases in the Czech Republic.

    Area of Science:

    • Pediatric critical care medicine
    • Infectious diseases
    • Rheumatology

    Background:

    • COVID-19 predominantly causes mild illness in children.
    • A subset of pediatric COVID-19 cases can develop Paediatric Inflammatory Multisystem Syndrome (PIMS).
    • PIMS presents with diverse symptoms including fever, gastrointestinal issues, neurological signs, and multiorgan dysfunction.

    Purpose of the Study:

    • To report the initial cases of critically ill pediatric patients with PIMS in the Czech Republic.
    • To highlight the clinical presentation and severity of PIMS in a pediatric population.

    Main Methods:

    • Case series reporting on three critically ill pediatric patients.
    • Clinical data collection including symptoms, disease course, and management.

    Main Results:

    • Three pediatric patients presented with severe PIMS following SARS-CoV-2 infection.
    • Patients exhibited symptoms such as high fever, gastrointestinal distress, neurological involvement, and multiorgan dysfunction.
    • These represent the first documented critically ill pediatric PIMS cases in the Czech Republic.

    Conclusions:

    • PIMS is a significant, albeit rare, complication of COVID-19 in children requiring intensive care.
    • Early recognition and management are crucial for pediatric patients with severe PIMS.
    • This report underscores the importance of monitoring for PIMS in pediatric COVID-19 cases.

    Keywords:
    COVID-19inflammatory syndromepaediatric patient

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