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Sjogren's syndrome-An interesting case.
Rakesh K Chawla1, Aditya K Chawla1, Gaurav Chaudhary1
1Department of Pulmonary Medicine, Critical Care and Sleep disorders, Jaipur Golden Hospital, Saroj Super Speciality Hospital, 36, Pocket: E-3, Sector-3, Rohini, New Delhi, 110085, India.
The Indian Journal of Tuberculosis
|January 25, 2022
Summary
This case report highlights a 50-year-old female with Sjogren syndrome, focusing on her pulmonary manifestations. Early diagnosis and management with steroids and supportive care led to significant improvement.
Area of Science:
- Rheumatology
- Pulmonology
- Immunology
Background:
- Sjogren syndrome (SS) is a chronic autoimmune disorder primarily affecting exocrine glands.
- Extraglandular manifestations, including pulmonary involvement, are common in SS.
- Early recognition and management are crucial for improving patient outcomes.
Observation:
- A 50-year-old female presented with dry eyes, reduced salivation, dysphagia, persistent dry cough, and progressive dyspnea.
- Diagnostic workup revealed positive anti-Ro/SS-A and anti-La/SS-B antibodies.
- Histopathological examination of a sublingual biopsy confirmed Sjogren syndrome.
Findings:
- The patient exhibited significant pulmonary symptoms, including dyspnea and dry cough.
- Treatment with oral glucocorticoids, hydroxychloroquine (HCQS), artificial tears, and iron supplements resulted in marked clinical improvement.
- Regular follow-up indicated sustained positive response to treatment.
Implications:
- This case underscores the importance of considering Sjogren syndrome in patients with unexplained pulmonary symptoms and sicca symptoms.
- Prompt diagnosis through serological and histopathological evaluation is key.
- Multidisciplinary management, including immunosuppressants and supportive therapies, can effectively control extraglandular manifestations like pulmonary involvement in Sjogren syndrome.
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