Related Experiment Video
Updated: Oct 5, 2025

Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
A framework for estimating and visualising excess mortality during the COVID-19 pandemic
Garyfallos Konstantinoudis1, Virgilio Gómez-Rubio2, Michela Cameletti3
1MRC Centre for Environment and Health, Imperial College London, St Mary's Campus, Praed St, W2 1NY, London United Kingdom.
COVID-19 deaths undercount the pandemic's true toll. Excess mortality, comparing observed to expected deaths, offers a more accurate measure. This study presents an R framework for high-resolution excess mortality estimation and visualization.
Area of Science:
- Epidemiology
- Biostatistics
- Public Health
Background:
- COVID-19 mortality data often lack completeness and accuracy, underestimating the pandemic's impact.
- Excess mortality, a comparison of observed versus expected deaths, provides a more robust metric for pandemic burden.
- Accurate, high-resolution data are crucial for understanding within-country trends and evaluating public health interventions.
Approach:
- Propose a flexible R framework for estimating and visualizing excess mortality at high geographical resolution.
- Demonstrate the framework with a case study of excess deaths in Italy during 2020.
- The framework integrates various models and allows flexible aggregation of results by age, sex, space, and time.
Key Points:
- Excess mortality estimation requires accounting for population trends, temperature, and spatio-temporal factors.
- The R framework enables rapid implementation and adaptable analysis of excess mortality data.
- High geographical resolution is essential for granular analysis of pandemic impact and policy effectiveness.
Conclusions:
- The proposed R framework offers a powerful tool for online monitoring of the pandemic's mortality burden.
- Timely and accurate excess mortality data facilitate informed policy-making and public health responses.
- This approach enhances the ability to assess the true impact of the pandemic across diverse populations and regions.
Related Concept Videos
Statistical Methods for Analyzing Epidemiological Data
Kaplan-Meier Approach
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
Causality in Epidemiology
Design Example: Analyzing Capacity Contours for Flood Risk Assessment
Steps in Outbreak Investigation

