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[High prenatal detection rates of complex congenital heart defects (CHD)]

Katrin Fricke1, Misha Bhat2, Vasileios Avdikos3

  • 1med dr, bitr överläkare, barn- och fetalkardiolog, Barnhjärtcentrum, Skånes universitetssjukhus Lund.

Lakartidningen
|January 26, 2022
PubMed

Insights

Prenatal screening for complex congenital heart defects (CHD) achieved high detection rates using a three-tiered model. This approach improved identification of critical heart conditions in newborns.

Area of Science:

  • Obstetrics and Gynecology
  • Pediatric Cardiology
  • Medical Imaging

Background:

  • Congenital heart defects (CHD) are a significant concern in prenatal care.
  • Effective prenatal screening is crucial for timely intervention and improved outcomes.
  • The Skane University Hospitals implemented an expanded three-tiered screening model in 2015.

Purpose of the Study:

  • To evaluate the prenatal detection rates of complex congenital heart defects (CHD).
  • To assess the effectiveness of an expanded three-tiered screening model.
  • To analyze detection rates after the model's implementation in 2015.

Main Methods:

  • Retrospective review of pregnancies screened between January 1, 2015, and June 30, 2018.
  • Definition of complex CHD as conditions requiring intervention within the first year of life.
  • Analysis of detection rates for various types of complex CHD.

Main Results:

  • Out of 27,675 screened pregnancies, 51 of 65 (78%) complex CHD cases were detected prenatally.
  • Excluding isolated ventricular septal defects, detection rates increased to 93%.
  • High detection rates (approx. 90%) were observed for critical conditions like tetralogy of Fallot, atrioventricular septal defect, and coarctation.

Conclusions:

  • The implemented three-tiered screening model demonstrates high detection rates for complex CHD.
  • This model optimizes resource utilization in prenatal screening.
  • The strategy effectively identifies critical congenital heart defects, enabling prompt management.
Abstract

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