OCT ANGIOGRAPHY, VISUAL FIELD AND RNFL WITH VARIOUS MEDICATIONS IN HYPERTENSIVE GLAUCOMAS

Area of Science:

• Ophthalmology
• Glaucoma Research
• Optometry

Background:

• Hypertensive glaucoma (HTG) poses a risk for optic nerve damage.
• Understanding treatment effects on visual parameters is crucial for patient management.
• Current research explores the impact of various therapeutic agents on HTG progression.

Purpose of the Study:

• To evaluate the impact of different treatment strategies on visual field and retinal nerve fiber layer (RNFL) in patients with hypertensive glaucoma (HTG).
• To determine if combination therapy, beta-blockers, or prostaglandin analogs lead to significant changes in ocular parameters.

Main Methods:

• A cohort of 36 HTG patients was divided into three groups receiving combination therapy, beta-blockers, or prostaglandin analogs.
• Retinal nerve fiber layer (RNFL) and vessel density (VD) were measured using optical coherence tomography (OCT).
• Visual field defects were assessed using standard perimetry, with statistical analysis adjusted for age and gender.

Main Results:

• Combination therapy demonstrated statistically significant differences in visual field parameters (p = 0.0006).
• Beta-blocker treatment showed significant differences in RNFL measurements (p = 0.04).
• Prostaglandin analog group served as the baseline for comparison.

Conclusions:

• Combination therapy in HTG patients may lead to detectable changes in visual field function.
• Beta-blocker treatment can influence RNFL thickness in HTG.
• Further research is warranted to elucidate the long-term effects of these treatments on glaucoma progression.