Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

¹H NMR: Long-Range Coupling01:27

¹H NMR: Long-Range Coupling

2.0K
The coupling interactions of nuclei across four or more bonds are usually weak, with J values less than 1 Hz. While these are usually not observed in spectra, the presence of multiple bonds along the coupling pathway can result in observable long-range coupling.
In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional Analyses in Patient-Derived Neurons Establish Pathogenicity for <i>STXBP1</i> Splice Variant c.429+5G>A.

Human mutation·2026
Same author

Qualitative EEG abnormalities in ASD reflect inhibition-dominated brain dynamics.

Scientific reports·2026
Same author

Dimensionality reduction of quantitative EEG and clinical profiles uncover associations with monogenic neurodevelopmental phenotypes in SNAREopathies.

Frontiers in neuroscience·2026
Same author

Critical Dynamics in the Association Cortex Predict Higher Intelligence in Typically Developing Children.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Human Neocortical Glutamatergic Neurons Revealed Through Multimodal Profiling.

bioRxiv : the preprint server for biology·2026
Same author

Altered Mechanical Properties of Astrocytes Lacking MLC1: Implications for the Leukodystrophy MLC.

Glia·2025

Related Experiment Video

Updated: Oct 5, 2025

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging
10:25

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging

Published on: June 5, 2017

14.2K

Long-Range Amplitude Coupling Is Optimized for Brain Networks That Function at Criticality.

Arthur-Ervin Avramiea1, Anas Masood1, Huibert D Mansvelder1

  • 1Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Amsterdam Neuroscience, VU Amsterdam, Amsterdam 1081 HV, The Netherlands.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|January 27, 2022
PubMed
Summary

Criticality, a brain network state, optimizes neuronal coupling and information transfer. This dynamical state, characterized by scale-free oscillations, is crucial for efficient brain communication and function.

Keywords:
critical brain dynamicsexcitation-inhibition balancelong-range coupling

More Related Videos

Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis
05:59

Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis

Published on: October 6, 2023

2.8K
Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study
04:44

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study

Published on: July 21, 2021

4.4K

Related Experiment Videos

Last Updated: Oct 5, 2025

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging
10:25

Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging

Published on: June 5, 2017

14.2K
Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis
05:59

Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis

Published on: October 6, 2023

2.8K
Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study
04:44

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study

Published on: July 21, 2021

4.4K

Area of Science:

  • Computational Neuroscience
  • Network Science
  • Systems Neuroscience

Background:

  • Brain function relies on integrating and segregating information across networks.
  • Neuronal oscillations coordinate distributed processing via amplitude and phase coupling.
  • Local network properties optimizing functional connectivity remain poorly understood.

Purpose of the Study:

  • To investigate if criticality optimizes neuronal network coupling and information transfer.
  • To determine the role of criticality in amplitude and phase coupling of oscillations.
  • To explore how synaptic gain modulation affects network dynamics and information processing.

Main Methods:

  • Simulated in silico neuronal networks with α band oscillations (8-16 Hz).
  • Varied excitatory and inhibitory connectivity to modulate criticality.
  • Analyzed phase and amplitude coupling, and information transfer rates.

Main Results:

  • Phase coupling of oscillations emerged at criticality.
  • Amplitude coupling and information transfer were maximal at criticality.
  • Modulating synaptic gain to achieve critical dynamics optimized network coupling and information transfer.

Conclusions:

  • Criticality optimizes neuronal network coupling and information transfer.
  • Critical dynamics, not just static connection ratios, are key for efficient brain communication.
  • Findings may explain impaired long-range synchrony in brain disorders with altered local criticality.