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Updated: Oct 5, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
SARS-CoV-2 Omicron emergence urges for reinforced One-Health surveillance
Xavier Montagutelli1, Sylvie van der Werf2,3, Felix A Rey4
1Mouse Genetics Laboratory, Institut Pasteur, Université de Paris, Paris, France.
Abstract:
SARS-CoV-2 Omicron harbors substitutions in the receptor binding domain of the spike which strongly suggest its capacity to infect rodents. Wild animal reservoirs could favor the emergence of new variants with risks of spillback to humans and should be closely monitored.
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