Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

869
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
869
Clinical Trials01:16

Clinical Trials

9.5K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
9.5K
Clinical Trials: Overview01:11

Clinical Trials: Overview

3.7K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.7K
Blind Procedures02:07

Blind Procedures

12.3K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
12.3K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

190
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
190
Guidelines and Strategies for Safe Computer Charting01:18

Guidelines and Strategies for Safe Computer Charting

942
The guidelines and strategies provided by the American Nurses Association (ANA) and the Canadian Nurses Association (CNA) offer essential principles for ensuring safe and secure computer charting systems in healthcare settings. Let's break down each recommendation:
Maintain Confidentiality and Security:
942

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Central Nervous System Toxoplasmosis is an Under-Recognized Opportunistic infection in Uganda.

Journal of tropical medicine·2026
Same author

Cerebrospinal fluid transcriptional immune pathways linked to survival in HIV-associated tuberculous meningitis.

The Journal of infectious diseases·2026
Same author

Investigation of human leukocyte antigen alleles as risk factors for cryptococcal disease in Ugandan individuals with HIV.

Human immunology·2026
Same author

Metformin on the Presence of COVID-19 Symptoms 6 Months after Infection: The ACTIV-6 Randomized Clinical Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Change in plasma cryptococcal antigen titers in Uganda among outpatients with advanced HIV disease from 2017 to 2022 with rollout of national cryptococcal screening.

PloS one·2026
Same author

Pulmonary Aspergillosis Treated With Oral Amphotericin B (MAT2203) in a Patient With HIV-Related Cryptococcal Meningitis.

Clinical case reports·2026

Related Experiment Video

Updated: Oct 5, 2025

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers
09:16

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

10.4K

Technical procedures and REDCap tools for internet-based clinical trials.

Ananta S Bangdiwala1, David R Boulware2

  • 1School of Public Health, University of Minnesota, Minneapolis, MN, USA.

Contemporary Clinical Trials
|January 27, 2022
PubMed
Summary
This summary is machine-generated.

Researchers explored hydroxychloroquine for COVID-19 (coronavirus disease 2019) prevention and treatment. They utilized Research Electronic Data Capture (REDCap) for remote data collection in these pragmatic clinical trials.

Keywords:
AutomationClinical trialsCovid-19Data base managementPatient-oriented researchSurvey

More Related Videos

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.5K
Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation
04:58

Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation

Published on: August 25, 2022

2.3K

Related Experiment Videos

Last Updated: Oct 5, 2025

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers
09:16

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

10.4K
E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.5K
Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation
04:58

Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation

Published on: August 25, 2022

2.3K

Area of Science:

  • Clinical research methodology
  • Infectious disease epidemiology
  • Pharmacological interventions

Background:

  • The emergence of COVID-19 necessitated rapid clinical trial development.
  • Remote data collection was crucial for low-touch, participant-reported studies.
  • Hydroxychloroquine was investigated for its potential prophylactic and therapeutic effects.

Purpose of the Study:

  • To describe the implementation of clinical trials for COVID-19.
  • To detail the use of Research Electronic Data Capture (REDCap) in remote, participant-reported studies.
  • To share challenges, choices, and suggestions for using REDCap in similar trials.

Main Methods:

  • Development and initiation of three clinical trials for hydroxychloroquine in March 2020.
  • Simultaneous creation of REDCap projects to support remote data collection.
  • Leveraging REDCap's features for pragmatic, internet-based research.

Main Results:

  • REDCap facilitated the management of low-touch, remote COVID-19 trials.
  • The platform's flexibility allowed for tailored solutions to trial-specific needs.
  • Participant-reported data collection was successfully implemented.

Conclusions:

  • REDCap is a valuable tool for conducting pragmatic, internet-based clinical trials.
  • Creative application of REDCap features can overcome challenges in remote research.
  • Experience gained can inform future remote trial designs for infectious diseases.