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Updated: Oct 5, 2025

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
Published on: July 7, 2023
[The new Parkinson's disease pain classification system (PD-PCS)]
V Mylius1,2,3, S Perez Lloret4, C S Brook5
1Klinik für Neurologie und Neurorehabilitation, Kliniken Valens, Valens, Schweiz. Veit.Mylius@kliniken-valens.ch.
Background:
Chronic pain is a common non-motor symptom in patients with Parkinson's disease (PD).
Aim:
To facilitate the diagnosis of pain in PD, we developed a new classification system the Parkinson's disease pain classification system (PD-PCS) and translated the corresponding validated questionnaire into German.
Methods:
A causal relationship of the respective pain syndrome with PD can be determined by four questions before assigning it hierarchically into one of three pain categories (neuropathic, nociceptive and nociplastic).
Results:
In the initial validation study 77% of the patients (122/159) had PD-associated pain comprising 87 (55%) with nociceptive, 36 (22%) with nociplastic and 24 (16%) with neuropathic pain. The study revealed a high validity of the questionnaire and a moderate intrarater and interrater reliability. The questionnaire has been adapted into German and employed in 30 patients.
Discussion:
The PD-PCS questionnaire is a valid and reliable tool to determine the relationship of a pain syndrome with PD before classifying it according to the underlying category, facilitating further diagnostics and treatment.
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