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Published on: August 19, 2013
Highly Selective Detection of Al3+ by Carboxamide-Based Fluorescent Chemosensor
Jae Sung Heo1, Dongkyun Gil1, Cheal Kim2
1Department of Fine Chem, SNUT (Seoul National Univ. of Sci. and Tech.), Seoul, 01078, Korea.
Abstract:
We designed a carboxamide-based fluorescent chemosensor HTPQ ((E)-2-(((8-hydroxy-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)methylene)amino)thiophene-3-carboxamide) for detecting Al3+. HTPQ could probe Al3+ by fluorescence enhancement. Limit of detection for Al3+ toward HTPQ was 1.4 μM. Binding of HTPQ to Al3+ was determined to be a 1:1 ratio with the analysis of Job plot and ESI-mass. In addition, HTPQ was able to detect Al3+ using the test strip by fluorescent variation. The sensing process of Al3+ by HTPQ was presented by UV-vis titration, ESI-MS, Job plot, 1H NMR titration and DFT calculation.
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