Micro and nanofluidics for high throughput drug screening

Area of Science:

• Biotechnology
• Medical Diagnostics
• Drug Discovery

Background:

• Advancements in high throughput screening (HTS) are crucial for efficient drug discovery.
• Microfluidics and nanofluidics offer miniaturized platforms for complex biological assays.
• Current drug screening methods face challenges in speed and cost-effectiveness.

Purpose of the Study:

• To review state-of-the-art technology developments in HTS, microfluidics, and nanofluidics.
• To elaborate on the application of microfluidics and nanofluidics for HTS in communicable and non-communicable diseases.
• To explore future perspectives and integration with emerging technologies.

Main Methods:

• Review of current literature on microfluidic and nanofluidic technologies for HTS.
• Analysis of applications in drug screening for various diseases, including cancer.
• Discussion of potential integration with Fourth Industrial Revolution (4IR) technologies.

Main Results:

• Microfluidics and nanofluidics are enabling advanced HTS for drug screening.
• These technologies show significant potential for applications in cancer precision medicine, point-of-care diagnostics, and medical imaging.
• Integration with 4IR technologies and digital health is poised to drive next-generation medical advancements.

Conclusions:

• Microfluidics and nanofluidics represent a significant technological leap in high throughput drug screening.
• Their application extends to critical areas like precision medicine and diagnostics.
• The convergence with 4IR technologies promises transformative developments in the medical field.