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Related Experiment Video

Updated: Oct 5, 2025

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Keratopigmentation: Is it a Miracle or an Adventure?

Melisa Zisan Karslioglu1, Ayse Yildiz Tas1, Cem Kesim1

  • 1Department of Ophthalmology, Koc University Hospital, Istanbul, Turkey.

Beyoglu Eye Journal
|January 31, 2022
PubMed
Summary

Keratopigmentation (KTP) offers a safe and effective cosmetic and functional improvement for eyes with severe vision impairment. This procedure demonstrates high patient satisfaction and minimal complications, making it a valuable alternative to more invasive treatments.

Keywords:
Corneal opacificationcorneal tattookeratopigmentation

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Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Ocular Aesthetics

Background:

  • Patients with severe corneal opacification or visual impairment often face limited cosmetic and functional options.
  • Traditional treatments may be invasive or unsuitable for individuals intolerant to prosthetic contact lenses.

Purpose of the Study:

  • To analyze the cosmetic and functional outcomes of patients undergoing keratopigmentation (KTP).
  • To evaluate patient satisfaction, pigment stability, and surgical complications associated with KTP.

Main Methods:

  • Analysis of 16 eyes from 16 patients who underwent manual intrastromal and superficial keratopigmentation under general anesthesia.
  • Inclusion criteria focused on patients with severe visual impairment (no or only light perception) and corneal opacification.
  • Outcomes assessed included patient satisfaction, cosmetic results, pigment stabilization, and complications using a 0-5 grading system.

Main Results:

  • High postoperative patient satisfaction reported, with a mean score of 4.18 out of 5.
  • Minor pigment loss occurred in some cases, requiring superficial KTP re-pigmentation in 2 patients; overall cosmetic results were satisfactory.
  • The procedure demonstrated a favorable safety profile with minimal complications, including one instance of pigment leakage.

Conclusions:

  • Keratopigmentation is a safe, easily learned, and cost-effective surgical technique.
  • KTP provides significant therapeutic and cosmetic benefits, potentially impacting future ophthalmic surgical practices.
  • It serves as a valuable alternative to more invasive reconstructive ocular procedures.