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Updated: Aug 5, 2026
07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Structure-Function Relationship in Patients with Glaucoma Suspect: Diagnostic Value and Changes During Follow-up
Zeynep Akgun1, Mine Esen Baris1, Suzan Guven Yılmaz1
1Department of Ophthalmology, Ege University, Faculty of Medicine, Izmir, Türkiye.
Beyoglu Eye Journal
|August 4, 2026
Summary
Glaucoma suspects showed no significant anatomical or functional changes over 12 months. Comprehensive evaluation of visual field (VF), retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) is crucial for diagnosis.
Area of Science:
- Ophthalmology
- Optometry
- Medical Imaging
Background:
- Glaucoma suspicion requires careful monitoring for anatomical and functional changes.
- Differentiating glaucoma suspects from early glaucoma necessitates sensitive diagnostic tools.
Purpose of the Study:
- To evaluate anatomical and functional changes in eyes with glaucoma suspicion over a 12-month follow-up period.
- To assess the utility of Optical Coherence Tomography (OCT) and Visual Field (VF) testing in monitoring glaucoma suspects.
Main Methods:
- 56 eyes of 28 patients underwent ophthalmologic examination, OCT, and VF (SITA 24-2 and 10-2) at baseline and 12 months.
- Retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses, VF global indices (MD, PSD), and hemi-quadrant sensitivities were recorded.
- Presence of "cluster defect" in VFs was noted.
Main Results:
- No significant changes in intraocular pressure (IOP) or cup/disc ratio (C/D) were observed.
- No significant progression was noted in OCT and VF parameters.
- Correlations were found between RNFL, GCC, and VF indices (MD, PSD), but not with 10-2 VF sensitivities.
Conclusions:
- No single parameter reliably differentiates glaucoma suspects from early glaucoma.
- Integrated evaluation of VF, RNFL, and GCC is recommended.
- Longer follow-up periods are necessary for definitive diagnosis.
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