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Andrés Sánchez-Pájaro1, Carolina Pérez Ferrer2, Ana Basto-Abreu3

  • 1Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública. Cuernavaca, Morelos, México.. andres.sanchez@insp.mx.

Salud Publica De Mexico
|January 31, 2022
PubMed
Summary

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This summary is machine-generated.

Obesity may increase susceptibility to SARS-CoV-2 infection, with higher seropositivity observed in individuals with obesity. No significant association was found between SARS-CoV-2 seropositivity and other chronic diseases in Mexican adults.

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Public Health

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has had a significant global impact.
  • Understanding risk factors for SARS-CoV-2 infection, including chronic diseases, is crucial for public health strategies.

Purpose of the Study:

  • To analyze the association between SARS-CoV-2 seropositivity and chronic diseases in Mexican adults and older adults.
  • To investigate the relationship between SARS-CoV-2 infection and hypertension, diabetes, obesity, and lipid profiles.

Main Methods:

  • Utilized data from the 2020 National Health and Nutrition Survey on COVID-19 (Ensanut 2020 Covid-19).
  • Assessed SARS-CoV-2 seropositivity in relation to systemic arterial hypertension, type 2 diabetes, body mass index, elevated LDL-c, low HDL-c, elevated total cholesterol, and hypertriglyceridemia.

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Main Results:

  • A higher prevalence of SARS-CoV-2 seropositivity was observed in individuals with a higher body mass index.
  • Adults with obesity showed a 25% greater seroprevalence compared to normal-weight individuals (RP: 1.25, 95% CI: 1.08, 1.46).
  • No significant association was found between SARS-CoV-2 seropositivity and other chronic conditions in adults or older adults.

Conclusions:

  • Obesity may be associated with increased susceptibility to SARS-CoV-2 infection.
  • Further longitudinal studies are needed to confirm the association between obesity and SARS-CoV-2 infection.
  • No evidence of association was found for other chronic diseases investigated.