Association of Gallbladder Volume and Wall Thickness With Acute Appendicitis in Pediatric Patients

Ahmet Yalcin1, Berrin Demir2, Muhammed Demir3

  • 1From the Department of Radiology, Faculty of Medicine, Erzincan University.

Pediatric Emergency Care
|February 1, 2022
PubMed

Insights

In pediatric patients, increased gallbladder volume during ultrasonography is linked to appendicitis, while thicker gallbladder walls may indicate its absence. These findings aid in diagnosing appendicitis when the appendix is not clearly visualized.

Area of Science:

  • Pediatric Radiology
  • Abdominal Imaging
  • Gastrointestinal Diagnostics

Background:

  • Ultrasonography is key for diagnosing appendicitis in children.
  • Secondary ultrasound findings are crucial when the appendix is not visualized.
  • Evaluating adjacent organs like the gallbladder can provide diagnostic clues.

Purpose of the Study:

  • To assess gallbladder wall thickness and volume in pediatric patients with suspected appendicitis.
  • To determine if gallbladder parameters correlate with appendicitis diagnosis.
  • To explore the utility of gallbladder measurements as secondary ultrasound markers.

Main Methods:

  • A prospective study included 113 pediatric patients with suspected appendicitis.
  • Radiologists measured gallbladder wall thickness, width, length, and height.
  • Appendix assessment was categorized as acute appendicitis, normal, or equivocal.
  • Statistical analysis sought associations between gallbladder metrics and appendicitis.

Main Results:

  • Gallbladder wall thickness was significantly higher in patients without appendicitis (P=0.017).
  • Gallbladder volume was significantly increased in patients with appendicitis (P=0.004).
  • Receiver operating characteristic analysis identified thresholds for gallbladder wall thickness (0.5 mm) and volume (41.6 mL) with high sensitivity and specificity.

Conclusions:

  • Gallbladder wall thickness and volume are associated with appendicitis diagnosis in pediatric patients.
  • These gallbladder measurements can serve as valuable secondary indicators in appendicitis diagnosis via ultrasound.
Abstract

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