Related Experiment Video
Updated: Oct 5, 2025
07:40
A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
Published on: August 30, 2019
9.1K
Iron Pill-Induced Chemical Laryngitis
Rishabh Sethia1, Ryan Bishop2, Adlin Gordian-Arroyo2
1Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
The Annals of Otology, Rhinology, and Laryngology
|February 1, 2022
Summary
This case study highlights iron pill-induced laryngitis, a rare condition causing severe dysphonia. Prompt diagnosis and management, including vocal fold injection, are crucial for recovery.
Area of Science:
- Otolaryngology
- Gastroenterology
Background:
- Pill-induced laryngitis is a rare condition, often linked to bisphosphonates.
- It presents as chemical injury to the larynx following pill aspiration.
Observation:
- A 71-year-old male experienced complete voice loss after aspirating an iron pill.
- Laryngoscopy revealed significant vocal fold and infraglottic inflammation, ulceration, and crusting.
- The patient also exhibited glottic insufficiency and suspected sensory deficit.
Findings:
- Treatment with nebulized antibiotics and humidified air improved mucosal crusting.
- Persistent glottic insufficiency necessitated bilateral hyaluronic acid injection for voice restoration.
Implications:
- This case broadens the spectrum of medications causing pill-induced laryngitis to include iron supplements.
- Early recognition and tailored management, potentially including vocal fold augmentation, are vital for patients with dysphonia and a history of pill aspiration.
Related Concept Videos
01:23Chronic Pharyngitis
5.9K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
5.9K
01:30Acute Pharyngitis
1.9K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
1.9K
01:30Peptic Ulcer Disease I: Introduction
321
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
321
01:30Other Disorders of Digestive System
1.1K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.1K
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
3.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
3.2K
01:30Tonsillitis I: Introduction
660
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
660