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Animal Mitochondrial Genetics

Animal Mitochondrial Genetics

Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...

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Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

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Human cleaving embryos enable efficient mitochondrial base-editing with DdCBE

Yinghui Wei^1,2, Chunlong Xu³, Hu Feng⁴

¹International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

|February 1, 2022

Summary

No abstract available in PubMed .

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