Individual Differences in Chemosensory Perception Amongst Cancer Patients Undergoing Chemotherapy: A Narrative Review

Area of Science:

• Oncology
• Sensory Science
• Nutritional Science

Background:

• Chemotherapy's toxicity often causes taste and smell alterations in cancer patients.
• These chemosensory changes can lead to malnutrition, hindering recovery and long-term well-being.
• Significant individual variability exists in the experience and intensity of these sensory side effects.

Purpose of the Study:

• To review the causes of individual differences in chemotherapy-induced chemosensory alterations.
• To encourage research into personalized approaches for managing these sensory issues.
• To propose strategies for improving food perception and nutritional status in cancer patients.

Main Methods:

• Narrative bibliographic review of existing literature.
• Analysis of potential causes for individual differences in sensory perception.
• Identification of potential interventions to improve chemosensory perception.

Main Results:

• Chemosensory alterations are a common but variable side effect of chemotherapy.
• Individual differences in perception and intensity are not well understood.
• Potential strategies for intervention exist but require further research.

Conclusions:

• Understanding individual differences in chemosensory perception is crucial for personalized cancer care.
• Further research is needed to elucidate the origins of these variations.
• Developing targeted strategies can mitigate malnutrition and improve quality of life for cancer patients.