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Market Formation in a Global Health Transition
Freek de Haan1, Ellen H M Moors1, Arjen M Dondorp2
1Copernicus Institute of Sustainable Development, Utrecht University, Princetonlaan 8a, 3484 CB, Utrecht, the Netherlands.
Drug-resistant malaria spurred the creation of Artemisinin-based Combination Therapies (ACT) markets. Public institutes, academia, and global organizations facilitated ACT development and deployment, forming crucial public and private markets in the Greater Mekong Subregion.
Area of Science:
- Health innovation systems
- Market formation studies
- Global health transitions
Background:
- Drug-resistant malaria presents a significant global health challenge.
- Innovation systems research is increasingly examining market formation dynamics.
- The Greater Mekong Subregion (GMS) faces persistent threats from drug-resistant malaria.
Purpose of the Study:
- To investigate the market formation process for Artemisinin-based Combination Therapies (ACT) in the GMS.
- To analyze the roles of various actors and scales in establishing ACT markets.
- To draw lessons for current and future malaria control efforts.
Main Methods:
- Qualitative analysis of market formation activities.
- Examination of innovation system development at global, national, and local scales.
- Case study focusing on ACT in the GMS.
Main Results:
- Public institutes, academia, and partnerships were vital in early innovation system development.
- Transnational organizations fostered a supportive global environment for ACT.
- Successful market formation of both public-sector and private-sector ACT occurred in the GMS.
- Structural couplings across scales enabled the functioning of the global innovation system.
Conclusions:
- Market formation for health innovations is a multi-scalar process.
- Collaborative efforts involving diverse stakeholders are essential for developing and deploying new therapies.
- Understanding past market formation is critical for addressing the resurgence of drug-resistant malaria and developing new treatments.
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