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Published on: June 20, 2020
Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection
Tomoaki Yamasaki1, Yuhei Sakata1, Takehisa Suekane1
1Department of Gastroenterology, Osaka City General Hospital, Japan.
Abstract:
Although dexmedetomidine (DEX) is a widely used analgesic and sedative agent for endoscopic procedures, cardiovascular complications, such as bradycardia and hypotension, are frequently experienced. We herein report the first case of asystole-induced bradycardia due to DEX during endoscopic submucosal dissection (ESD). An 81-year-old man without cardiovascular diseases was referred for gastric carcinoma. ESD was started after administering a loading dose of DEX followed by a continuous maintenance infusion of DEX. The patient's heart rate gradually decreased, and then cardiac arrest occurred. DEX has a risk of cardiac arrest, so bradycardia should not be underestimated during sedation with DEX.
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