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Updated: Oct 4, 2025

Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
Published on: September 29, 2015
Role of Plasma-rich Fibrin in the Management of Intrusion Injuries of Teeth
Rajesh Ragulakollu1, Nandini Biradar2, Gururam T Kukkunuru3
1Department of Pedodontics and Preventive Dentistry, Malla Reddy Institute of Dental Sciences, Hyderabad, Telangana, India.
Aim And Objective:
To establish a new method of treating severe type of intrusion type of injuries to teeth. The prognosis of these injuries is poor. Poor prognosis is attributed to the development of multiple complications from various components of teeth. We described the various phases to prevent and treat various complications.
Background:
Most common sequelae to intrusion injuries are alveolar bone loss, resorption of teeth, and gingival recession. Plasma-rich fibrin (PRF) possesses various biological elements for optimal healing and prevention of the above.
Case Description:
A 9-year-old female patient suffered intrusion injury to 21 with no root fractures. Since intrusion was severe type, surgical repositioning with flexible splinting is done. Complications such as alveolar bone loss and gingival recession have occurred, which were successfully treated with PRF. To prevent development of resorption, calcium hydroxide was used as intracanal medicament and doxycycline was used to prevent surface resorption.
Conclusion:
PRF is effective not only in promoting healing, bone deposition but also prevents secondary infection of the wound. Hence, it is simple, easy, and inexpensive biomaterial for treating intrusion injuries of teeth.
Clinical Significance:
Considering the various properties associated with PRF, it could be a key for treating other type traumatic injuries to teeth.
How To Cite This Article:
Ragulakollu R, Biradar N, Kukkunuru GT, et al. Role of Plasma-rich Fibrin in the Management of Intrusion Injuries of Teeth. Int J Clin Pediatr Dent 2021;14(6):820-824.
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