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Cryptococcus gattii endogenous chorioretinitis.

Keirnan L Willett1, Lauren A Dalvin1, Bobbi S Pritt2

  • 1Mayo Clinic, Department of Ophthalmology, Rochester, MN, USA.

American Journal of Ophthalmology Case Reports
|February 3, 2022
PubMed
Summary
This summary is machine-generated.

Cryptococcus gattii, a fungus, can cause eye infections like subretinal abscesses in healthy individuals. This case highlights its potential role in vision loss, alongside pneumonia and meningitis.

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ChorioretinitisCryptococcus

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Mycology

Background:

  • Cryptococcus gattii is an emerging fungal pathogen.
  • While Cryptococcus neoformans commonly causes ocular infections, C. gattii is a less common cause.
  • Ocular cryptococcosis typically affects immunocompromised individuals.

Observation:

  • A 37-year-old immunocompetent male presented with painless unilateral vision loss.
  • Ophthalmic examination revealed a subretinal abscess in the macula.
  • Systemic workup identified concurrent pneumonia and meningitis due to Cryptococcus gattii.

Findings:

  • This case demonstrates Cryptococcus gattii as a cause of subretinal abscess in an immunocompetent host.
  • The fungal infection led to significant vision impairment.
  • Optical coherence tomography (OCT) was crucial in assessing retinal involvement.

Implications:

  • Cryptococcus gattii should be considered in the differential diagnosis of subretinal abscesses, even in immunocompetent patients.
  • Early diagnosis and treatment are essential to prevent vision loss.
  • Surgical intervention for submacular abscesses can be complex, requiring advanced imaging for guidance.