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Pediatric coccidioidal orbital granuloma.
Cassiana E Bittencourt1, Onyinye Okezie2, Khalid Tawansy3
1Department of Pathology and Laboratory Medicine, University of California Irvine, School of Medicine, Irvine, CA, USA.
American Journal of Ophthalmology Case Reports
|February 3, 2022
Summary
Orbital coccidioidomycosis, a rare fungal infection, was diagnosed in an 11-month-old boy. Prompt surgical drainage and antifungal treatment led to complete recovery without systemic involvement.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Background:
- Orbital infections can present with varied symptoms.
- Coccidioidomycosis is a fungal infection endemic to specific regions.
Observation:
- An 11-month-old male presented with orbital swelling, erythema, and pain.
- Initial conservative treatment and antibiotics were ineffective.
- Ultrasound revealed an orbital mass, leading to surgical drainage.
Findings:
- Culture, histopathology, and serology confirmed Coccidioides spp. infection.
- The patient experienced complete symptom resolution after surgical intervention and oral fluconazole.
Implications:
- Orbital coccidioidomycosis can occur as a primary manifestation of infection.
- Early consideration of fungal etiology is crucial in endemic areas, even after minor trauma.

