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Related Concept Videos

Proteomics01:33

Proteomics

8.4K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Protein Networks02:26

Protein Networks

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An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
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Protein-protein Interfaces02:04

Protein-protein Interfaces

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Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
13.9K

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Related Experiment Video

Updated: Oct 4, 2025

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics
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JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics

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Plant Proteomics and Systems Biology.

Flavia Vischi Winck1,2, André Luis Wendt Dos Santos3, Maria Juliana Calderan-Rodrigues4

  • 1Institute of Chemistry, University of São Paulo, São Paulo, Brazil. winck@cena.usp.br.

Advances in Experimental Medicine and Biology
|February 3, 2022
PubMed
Summary

Plant proteomics is expanding with new technologies for analyzing protein changes. This research enhances understanding of plant development and stress responses, crucial for crop performance in a changing environment.

Keywords:
2-DEExpressionMass spectrometryProteinQuantitative

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Area of Science:

  • Plant science
  • Proteomics
  • Systems biology

Background:

  • Proteome analysis in plants is a rapidly growing scientific field.
  • Technological advancements enable detailed qualitative and quantitative analysis of cellular responses at the protein level.

Purpose of the Study:

  • To highlight the advancements in proteomics for plant research.
  • To emphasize the role of proteomics in understanding plant development and environmental stress responses.
  • To showcase the utility of proteomics for improving crop performance.

Main Methods:

  • Time-resolved experiments
  • Multiplexed proteome analysis (chemical/isotopic labeling, label-free approaches)
  • Targeted and untargeted proteomics

Main Results:

  • Generation of vast proteomics data essential for post-translational modification analysis and systems biology.
  • Improved proteome identification completeness through combined targeted and untargeted methods.
  • Revealing nuanced regulatory cellular mechanisms in plant development and stress responses.

Conclusions:

  • Proteomic advancements, coupled with genomics and data analysis, enrich biological information beyond model plants.
  • Proteomics is a vital tool for understanding plant responses to environmental changes.
  • This field is critical for enhancing crop performance in the face of environmental challenges.