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Zebrafish and idiopathic scoliosis: the 'unknown knowns'
Ziyang Liu1, Yong Hai1, Zhuoran Li2
1Department of Orthopedics, Capital Medical University, Beijing, China; Department of Orthopedic Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Trends in Genetics : TIG
|February 4, 2022
Abstract:
The etiology and heterogeneity of idiopathic scoliosis (IS) are poorly understood. Studies using scoliotic zebrafish models have indicated a potential link between ciliary defects and scoliosis. They may further explain the onset of IS partially. However, it is necessary to further interpret the link between this progress and clinical medicine.
