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Updated: Oct 4, 2025

A BW Reporter System for Studying Receptor-Ligand Interactions
Published on: January 7, 2019
RBAC and Its Role with the Immune System
Context:
Rice Bran Arabinoxylan Compound (RBAC) is a trusted and proven immunomodulator made from a rice bran extract that has been enzymatically modified with an enzyme complex from the shiitake mushroom.
Objective:
The study's primary objective was to identify the role of RBAC in supporting cancer therapies.
Design:
The author designed an open study.
Participants:
Participants were 14 patients who are suffering from various type of malignancies.
Intervention:
BRM4 capsules-a commercially available, proprietary RBAC supplement-were administered.
Outcome Measures:
The study measured circulating tumor cells (CTC) and tumor markers-the prostate-specific antigen (PSA) and cancer antigens 125 (CA125) 15-3 (CA15-3), and 27-29 (CA27-29) for the relevant malignancy.
Results:
Twelve out of 14 participants completed the protocol, and two participants died during the study. Of the 12 participants completing the study, the CTC levels were reduced in 10, with a statistically significant difference between the testing at baseline and postintervention (P = .0047). The tumor markers of various malignancies decreased for nine out the 12 participants, and one participant experienced remission.
Conclusions:
The results suggest that the product can be an effective immunomodulator that can complement conventional cancer treatment.
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