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White blood cell count and differential count.

H A Werman, C G Brown

Emergency Medicine Clinics of North America

|February 1, 1986

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This review covers current white blood cell count and differential count methods, including new technologies. It also addresses potential errors and variations, and their clinical applications.

Area of Science:

Hematology
Clinical Pathology
Laboratory Medicine

Background:

The white blood cell count (WBC) and differential count are fundamental hematological tests.
Accurate interpretation relies on understanding current methodologies and potential sources of error.

Purpose of the Study:

To discuss current techniques for white blood cell count and differential count.
To highlight recent technological advancements in these assays.
To review sources of error and variation impacting test results.

Main Methods:

Literature review of current practices in white blood cell counting.
Analysis of recent technological innovations in hematology diagnostics.
Examination of factors contributing to variability in WBC and differential counts.

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Main Results:

Current methods provide essential diagnostic information.
Technological advances are improving accuracy and efficiency.
Understanding error sources is crucial for reliable results.

Conclusions:

The white blood cell count and differential count remain vital diagnostic tools.
Ongoing technological progress enhances their clinical utility.
Awareness of pre-analytical and analytical variables is key for accurate patient assessment.