Evidence-based risk factors for major complications during Ramadan fasting in people with diabetes grouped under

Rahmatullah1, Muhammad Yakoob Ahmedani2, Abdul Basit2

  • 1Consultant Diabetologist and Endocrinologist, Bolan Medical Complex Hospital (B.M.C.H), Quetta, Pakistan.

Insights

Identifying risk factors for major complications in people with diabetes fasting during Ramadan is crucial. Key factors include male gender, certain medications, and pre-existing conditions, necessitating pre-Ramadan risk assessment.

Area of Science:

  • Endocrinology and Metabolism
  • Public Health
  • Clinical Diabetes Management

Background:

  • Ramadan fasting poses unique challenges for individuals with diabetes.
  • Understanding risk factors for complications during fasting is essential for patient safety.
  • The International Diabetes Federation Diabetes and Ramadan (IDF-DAR) risk stratification is a valuable tool.

Purpose of the Study:

  • To identify evidence-based risk factors for major complications during Ramadan fasting in people with diabetes.
  • To stratify participants into IDF-DAR risk categories to guide risk assessment.
  • To inform preventative strategies for managing diabetes during Ramadan.

Main Methods:

  • Prospective observational multicenter study conducted from April to June 2019.
  • Recruitment of 1045 individuals with diabetes intending to fast during Ramadan.
  • Pre-Ramadan assessment including demographic data, risk categorization, and structured education; post-Ramadan assessment of complications.

Main Results:

  • Two-thirds of participants were categorized as very high- or high-risk.
  • Frequencies of major hypoglycemia, major hyperglycemia, hospitalization, and breaking the fast were 4.4%, 10.8%, 0.8%, and 3.1%, respectively.
  • Identified risk factors included male gender, sedatives/antidepressants, type 1 diabetes (hypoglycemia); history of DKA/HHS (hyperglycemia, hospitalization); older age, acute illness (hospitalization).

Conclusions:

  • Evidence-based risk factors for major Ramadan fasting-related complications in people with diabetes were identified.
  • Pre-Ramadan risk assessment is imperative to recognize and mitigate these identified factors.
  • This study provides crucial insights for optimizing diabetes care during Ramadan.
Abstract

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