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Updated: Oct 4, 2025

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Splenic Uptake in 99 mTc-Methylene Di-Phosphonate Scan in a Pediatric Patient with Acute Lymphocytic Leukemia
Himanshu Jaiswal1, Anshul Sharma1, Ravinder Singh Sethi1
1Department of Nuclear Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Abstract:
An 12-year-old boy with relapse of acute lymphocytic leukemia and suspected skeletal involvement underwent mTc-Methylene Di-Phosphonate skeletal scintigraphy, which revealed a lytic "cold" lesion in the pelvis and diffuse splenic uptake. There was no active splenic infiltration in cross-sectional imaging. However, the patient had a history of multiple blood transfusions, which is a rare cause for diffuse splenic uptake.
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