Related Experiment Video
Updated: Jul 4, 2026

A Simple Critical-sized Femoral Defect Model in Mice
Published on: March 15, 2015
Slipped Capital Femoral Epiphysis Associated with Endocrinopathy: A Narrative Review
K Aaron Shaw1, A Luke Shiver2, Tannur Oakes1
1Dwight D. Eisenhower Army Medical Center, Fort Gordon, Georgia.
»:
Slipped capital femoral epiphysis (SCFE) has a well-documented association with underlying endocrine conditions, including thyroid hormone aberrations and parathyroid dysfunction.
»:
Recombinant growth hormone therapy has also been identified as a risk factor for the development of SCFE.
»:
Presentation before their 10th birthday or after their 16th birthday along with height of <10th percentile are reliable risk factors for identifying children with an SCFE who are at a heightened risk for an underlying endocrinopathy and can been used to guide selective laboratory testing.
»:
Patients with unilateral SCFE presentations with an underlying endocrinopathy are at a heightened risk for contralateral slip development and should be treated with prophylactic fixation.
Related Concept Videos
Bones of the Lower Limb: Femur and Patella
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Nephrotic Syndrome I : Introduction
Chronic Kidney Disease II: Clinical Manifestations
Type I Diabetes III: Clinical Manifestations
Diabetic Nephropathy

