Related Experiment Video
Updated: Oct 4, 2025

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
Published on: December 27, 2024
Gastric Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
Jaffer A Ajani1, Thomas A D'Amico2, David J Bentrem3
11The University of Texas MD Anderson Cancer Center.
Advanced gastric cancer treatment is guided by biomarkers like HER2, MSI, and PD-L1. Targeted therapies and palliative care improve outcomes for patients with advanced or metastatic disease.
Area of Science:
- Oncology
- Gastroenterology
Background:
- Gastric cancer is a leading cause of cancer death globally, often diagnosed at advanced stages.
- Most gastric cancers are adenocarcinomas, classified by location and histology.
Purpose of the Study:
- To outline the management of unresectable locally advanced, recurrent, or metastatic gastric cancer.
- To highlight the role of biomarker testing and targeted therapies.
Main Methods:
- Review of NCCN Guidelines for Gastric Cancer.
- Focus on systemic therapy, palliative management, and multidisciplinary care.
Main Results:
- Biomarker testing (HER2, MSI, PD-L1) significantly impacts clinical practice.
- Targeted therapies (trastuzumab, nivolumab, pembrolizumab) show promise in clinical trials.
Conclusions:
- Systemic therapy offers palliation and improved survival for advanced gastric cancer.
- Palliative and multidisciplinary management are crucial for unresectable or metastatic disease.
More Related Videos
Related Concept Videos
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Chronic Pancreatitis II: Collaborative Care
Assessment:
Acute Pancreatitis II: Clinical Manifestations and Management

